Papers

I’m a scientist - group leader working at the intersection of genomics, computational biology, target discovery…

You can find my CV on LinkedIn and a complete list of publications on Google Scholar.

Publications for the last 10 years

2024

Midbrain Dopaminergic Neuron Development is Regulated by Two Molecularly Distinct Subtypes of Radial Glia Cells

Ásgrímsdóttir ES, Bassini LF, di Val Cervo PR, Gyllborg D, Pastor CP, Lee K, Grigsby C, Islam S, Lönneberg P, Villaescusa C, et al.

bioRxiv (2024)

The perineurium integrates leptin with its sympathetic outflow to protect against obesity

Sarker G, Habermann E, Chandran A, Monfeuga T, Maroteau C, Lundh S, Raimondi A, Martínez Sánchez N, Arús B, Iannacone M, et al.

bioRxiv (2024)

2023

Hepatocyte mARC1 promotes fatty liver disease

Lewis LC, Chen L, Hameed LS, Kitchen RR, Maroteau C, Nagarajan SR, Norlin J, Daly CE, Szczerbinska I, Hjuler ST, et al.

JHEP Reports 5(5) (2023)

2022

TCF7L2 plays a complex role in human adipose progenitor biology, which might contribute to genetic susceptibility to type 2 diabetes

Verma M, Loh NY, Sabaratnam R, Vasan SK, van Dam AD, Todorčević M, Neville MJ, Toledo E, Karpe F, Christodoulides C, et al.

Metabolism 133 (2022)

2020

Srebf1 controls midbrain dopaminergic neurogenesis

Toledo EM, Yang S, Gyllborg D, Van Wijk KE, Sinha I, Varas-Godoy M, Grigsby CL, Lönnerberg P, Islam S, Steffensen KR, et al.

Cell Reports 31(5) (2020)

2018

A Zeb2-miR-200c loop controls midbrain dopaminergic neuron neurogenesis and migration

Yang S, Toledo EM, Rosmaninho P, Peng C, Uhlén P, Castro DS, Arenas E

Communications Biology 1(1) (2018)

2017

Induction of functional dopamine neurons from human astrocytes in vitro and mouse astrocytes in a Parkinson’s disease model

Rivetti Di Val Cervo P, Romanov RA, Spigolon G, Masini D, Martín-Montañez E, Toledo EM, La Manno G, Feyder M, Pifl C, Ng YH, et al.

Nature Biotechnology 35(5) (2017)

Mapping genes for calcium signaling and their associated human genetic disorders

Hörtenhuber M, Toledo EM, Smedler E, Arenas E, Malmersjö S, Louhivuori L, Uhlén P

Bioinformatics 33(16) (2017)

Niche-derived laminin-511 promotes midbrain dopaminergic neuron survival and differentiation through YAP

Zhang D, Yang S, Toledo EM, Gyllborg D, Saltó C, Carlos Villaescusa J, Arenas E

Science Signaling 10(493) (2017)

2016

A PBX1 transcriptional network controls dopaminergic neuron development and is impaired in Parkinson’s disease

Villaescusa JC, Li B, Toledo EM, Rivetti di Val Cervo P, Yang S, Stott SRW, Kaiser K, Islam S, Gyllborg D, Laguna-Goya R, et al.

The EMBO Journal 35(18) (2016)

Molecular diversity of midbrain development in mouse, human, and stem cells

La Manno G, Gyllborg D, Codeluppi S, Nishimura K, Salto C, Zeisel A, Borm LE, Stott SRW, Toledo EM, Villaescusa JC, et al.

Cell 167(2) (2016)

2015

Anti-ribosomal P protein autoantibodies from patients with neuropsychiatric lupus impair memory in mice

Bravo-Zehnder M, Toledo EM, Segovia-Miranda F, Serrano FG, Benito MJ, Metz C, Retamal C, Alvarez A, Massardo L, Inestrosa NC, et al.

Arthritis & Rheumatology 67(1) (2015)